Bal If your sticking with Gas for cooking & heating:
Gas Boilers
If your having the plumbing done all round the house then have 15mm minimum copper plumbing on heating circuits (avoid going smaller than this) you make things easier 10+ years down the line when you will most likely have to install a Air Source Heat pump if the 2030 ban on Gas Boilers does in fact come into effect.
Weather Compensation
You will almost certainly want to have Weather Compensation Controls fitted to whatever boiler you decide to go with. In a test by one of the major manufacturers (I can't recall which off the top of my head) these are supposed to save at least 10-15% on gas use. Most of this comes from the boiler not overshooting the desired temperature.
This shows what typically happens with boiler heating controls

This shows how Weather Compensation and Opentherm Controls work.

Opentherm Controls
Nest, EPH and Salus have Opentherm settings. Some Boiler Manufacturers have their own controls that are Opentherm.
HIVE, Drayton Wiser and TADO DO NOT HAVE OPENTHERM (Wiser says it does but it only works on specific boilers & Tado removed it from UK products for some reason).
BEWARE some manufacturers use their own version of opentherm and you cannot use 3rd party Opentherm controls with them
Boiler Flow & Return Temperatures
You want to get the "Return" temperature (the water coming back into the boiler) as low as possible. The lower the more efficient the boiler operates.
As you can see from the graph gas boilers only start condensing when the flow temperature is below 54'C. At this temperature they are about 87% efficient. If you can get the return to about 40'C then you are in the 92/93% region.

Underfloor Heating
Will automatically allow you to run lower Flow (Out) and Return (In) temperatures on your heating. Try and avoid using Underfloor Heating Manifolds - a well designed system should not need them.
Heating Zones
I will presume that you will have radiators upstairs as underfloor heating on the first floor is very unusual. So you will likely need to zone your system but if your house is well insulated from the refurbishment then you may find you rarely need to turn your heating on upstairs....
Separate Heating and Hot Water Temperature Settings
Importantly Weather Compensation has allows you to decouple your Heating & Hot Water temperatures (for Heat Only Boilers). System and Combi Boilers already have this functionality.
Usually you would see a Heat Only or System Boiler used in conjunction with a Hot Water Cylinder.
You can still use a Combi Boiler with a Hot Water Cylinder. This is called Hot Water Priority although not all manufacturers offer this functionality.
Hot Water Cylinder
Again you want to get your hot water RETURN temperature back to the boiler as low as possible so for your Hot Water Cylinder you will want to consider a couple of options:
Single Coil
Either go with a very large single hot water coil (this is inside the cylinder and transfers the heat from the boiler into the cylinder) or a dual coil system.
Dual Coil
Typically you would have 1 large coil (in the bottom of the cylinder), and 1 smaller/medium (in the top section). With only a gas boiler you would plumb these in series so that you are taking as much heat as possible out of the hot water loop to get the RETURN temp back to the boiler as close to 40'C as possible.
This setup would also allow you to, in the future, plumb a Heat Pump into the bottom coil instead. Heat Pumps, usually, operate at lower flow temperatures so need larger coils to allow for the heat transfer to occur.
Personally I would also look at having 2 x immersion elements if possible. One at/near the bottom, a second about 1/3 of the way down.
Then if you have solar and a solar immersion diverter fitted you can heat the top 1/3 first and then heat at the bottom afterwards. This would act like a Heat Battery and is a great use of excess solar rather than exporting.
Chatting to another member on here I was surprised at the, reasonable, cost of a custom cylinder from Newark Cylinders https://newarkcylinders.co.uk/ so maybe worth giving them a call to discuss this.
Octopus are advertising a new brand of cylinder
https://heatandhotwatercylinders.co.uk/works-with-octopus-energy/
Personally I find their website awful and pretty unhelpful. I want to know how they work and how they are plumbed etc etc
But from what I have been able to find out they operate at higher temperatures than normal so upto 75'C and then blend this hot water with your mains cold water to your achieve your desired temperature at your tap.
They still have 1 or 2 Coil Options (a single coil option is shown in red/blue in the image below) and then a secondary coil (shown in green) that draws its heat back from the hot water (the inverse of your heating coils from your boiler) and can be used to supplement your heating.

Electric Heating/Hot Water
Sunamp and other electric systems are great but only offer 100% efficiency.
If you did want to go electric then an Air Source Heat Pump would be a better option. Depending on whether you go for a normal Low Temperature, a Medium Temperature or High Temperature model you would see anywhere from 200-500% efficiency (typically around 350-420%).
Thermaskirt
I came across this last week and found it pretty interesting.
However it is NOT cheap
https://www.discreteheat.com/thermaskirt/products-and-information/what-is-thermaskirt.aspx
Solar PV
From the sounds of it your looking at large property.
The largest Hybrid Inverter GE offer is the 5kw. Gen 2 and Gen 3 will both take 15kw DC PV Peak in 2 strings of 7.5kw and have a maximum battery discharge rate of 3.6kw (this limitation occurs when using battery only). This is almost certainly not be enough to power a large home. You could pair this with a 9.2 battery.
To get around that restriction you could also install the AIO. This has a 13.2kw battery and a sustained 6kw ac discharge.
If cost & space weren't issues then I personally would look at 5kw Hybrid Gen 3, 9.2 Battery + AIO.
If you wanted something without those restrictions then I would probably look at Sunsynk.
All this is assuming you are on single phase.
If you have 3 phase supply into your house then until GE sort out their "magic Box" (can't recall what its actually called) you will want to avoid GE Kit.
Normally you could install 3 x Inverters + 3 x batteries on each of the phases of the 3 phase but GE kit doesn't currently work properly in this configuration.
You could go MyEnergi Libbi but you will pay about 30% more for a 5kw + 2 x 5kw batteries as you would for GE or Sunsynk. Three phase go 3 x 1 phase Sunsynk or straight up 3 phase Sunsynk SYNK-8K-SG04LP3 / SYNK-10K-SG04LP3 /
SYNK-12K-SG04LP3.
Here are the relevant links:
https://www.givenergy.co.uk/products
https://www.sunsynk.org/
https://www.myenergi.com/